In order to identify the normal range of blood and urine cadmium Ievels in Korean, blood cadmium (Cd-B) and creatinine adjusted cadmium (Cd-U (Cr)) and specific gravity adjusted urine cadmium (Cd-U (SG)) were analized in 403 Koreans (male: 160,
female:
243) who were not occupationally exposed to cadmium by atomic absorption spectrophtometry using Zeeman effect background correction.
@ES The summarized results were as follows:
@EN 1. Sample distribution patterns of blood and urine cadmium levels in 403 who were not occupationally exposed to cadmium were log-normal distribution.
2. While the Cd-B, Cd-U (Cr) and Cd-U (SG) of males were 0.18±0.10 (GM:0.16) ug/dl of Cd-B, 1.56±1.26 (GM:1.19) ug/g creatinine of Cd-U (Cr), 1.60±1.20 (GM: 1.28) ug/l of Cd-U (SG), those of females were 0.15±0.07 (GM:0.14) ug/dl of Cd-B,
2.68±2.19
(GM:1.87) ug/g creatinine of Cd-U (Cr), 1.95±1.42 (GM:1.48) ug/l of Cd-U (SG), respectively.
There was a statistically significant difference of three indices between sexes (p<0.01).
3. Cd-B, Cd-U (Cr), and Cd-U (SG) of both sexes were increased with increase of age. There were significant increase of Cd-B, Cd-U (Cr) and Cd-U (SG) by the increase of age.
4. While Cd-B (GM) and Cd-U (Cr) (GM) in smoker and nonsmoker of males were 0.17ug/dl, 1.21ug/g creatinine and 0.13ug/dl, 1.14ug/g creatinine, those of females were 0.18ug/dl, 3.79ug/g creatinine 0.14ug/dl, 1.71ug/dl, 1.71ug/g creatinine. There
was
statistically significant difference of three indices between sexes (p<0.001).
5. There was significant increase of Cd-B, Cd-U (Cr) and Cd-U (SG) in smoking males by the increase of calculated pack year.
6. In stepwise multiple regreassion analysis, using Cd-B, Cd-U (Cr) and Cd-U (SG) as a dependent variables and age, sex, smoking and blood pressure as an independent variables, smoking habits, age and sex were contributed to Cd-B, significantly
(p<0.001), age and sex were contributed to Cd-U (Cr) and Cd-U (SG) significantly (p<0.001).
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